Shweta Das, Shreya Chand Katoch


Traditional uses of plants and their extracts have been in use for centuries. Medicines from herbal origin is still an important choice of about 75-85% of the population of the world as they were and are the easiest source available for caring and looking after towards health. Pomelo is a specie acquired with medicinal properties, like pharmacognostical property, phytochemical property and pharmacological property. These properties which are observed and found in pomelo helps efficiently in the remedies for ailments and diseases like convulsive cough, hemorrhage, leprosy, epilepsy, hiccough, diarrhea, headache, asthma, etc. A thorough study and test examination was carried out on some notably activities of pharmacology like activity of anti-diabetic, activity of CNS, activity of analgesic, activity of anti-inflammatory and many more values of medicinal and herbal aspects.

Full Text:



• Ahmad, M. M., Iqbal, Z., Anjum, F. M., & Sultan, J. I. (2006). Genetic variability to essential oil composition in four citrus fruit species. Pakistan Journal of Botany, 38(2), 319.

• Anis, M. (1981). Flavonoid patterns of leaves of some citrus species and their hybrids. Plant biochemical journal.

• Arcas, M. C., Botía, J. M., Ortuño, A. M., & Del Río, J. A. (2000). UV irradiation alters the levels of flavonoids involved in the defence mechanism of Citrus aurantium fruits against Penicillium digitatum. European Journal of Plant Pathology, 106(7), 617-622.

• Aswanikumar, S., & Radhakrishnan, A. N. (1973). Studies on a peptidase acting on a synthetic collagenase substrate Developmental pattern in rat granuloma tissue and distribution of enzyme in the tissues of various animals. Biochimica et Biophysica Acta (BBA)-General Subjects, 304(1), 210-216.

• Baomin, F. (2000). Pei Yuehu Department of Traditional Chinese Medicines, Shenyang Pharmaceutical University, Shenyang 110015; Research on the Chemical Constituents of the Coumarins from Citrus grandis Osbeck [J]. JOURNAL OF SHENYANG PHARMACEUTICAL UNIVERSITY, 4.

• Barrion, A. S. A., Hurtada, W. A., Papa, I. A., Zulayvar, T. O., & Yee, M. G. (2014). Phytochemical composition, antioxidant and antibacterial properties of pummelo (Citrus maxima (Burm.)) Merr. against Escherichia coli and Salmonella typhimurium. Food and Nutrition Sciences, 5(09), 749.

• Barthe, G. A., & Stewart, I. (1985). Enzyme immunoassay (EIA) of endogenous cytokinins in citrus. Journal of agricultural and food chemistry, 33(2), 293-297.

• Burkill, I. H. (1966). A dictionary of the economic products of the Malay Peninsula. A Dictionary of the Economic Products of the Malay Peninsula., 2(2nd edition).D.J. Wang. “Studies on the constituents of the essential oil of four aromatic flowers.” K’o Hsueh Fa Chan YuehK’an 1979, 7: 1036-1048.

• Chen, Y. F., Tsai, H. Y., & Wu, T. S. (1995). Anti-inflammatory and analgesic activities from roots of Angelica pubescens. Planta medica, 61(01), 2-8.

• Cheong, M. W., Liu, S. Q., Yeo, J., Chionh, H. K., Pramudya, K., Curran, P., & Yu, B. (2011). Identification of aroma-active compounds in Malaysian pomelo (Citrus grandis (L.) Osbeck) peel by gas chromatography-olfactometry. Journal of Essential Oil Research, 23(6), 34-42.

• Chowdhury, M. R. H., Sagor, M. A. T., Tabassum, N., Potol, M. A., Hossain, H., &Alam, M. A. (2015). Supplementation of Citrus maxima peel powder prevented oxidative stress, fibrosis, and hepatic damage in carbon tetrachloride (CCl4) treated rats. Evidence-Based Complementary and Alternative Medicine, 2015.

• Danhi, R., & Weinstein, J. (2008). Southeast Asian flavors: adventures in cooking the foods of Thailand, Vietnam, Malaysia & Singapore. Mortar & Press.

• Dung, N. X., Pha, N. M., &Lô, V. N. (1992). The essential oils of flowers and fruit skin of two types of Citrus maxima from Doan Hung and Van Tri. Tap Chi Duoc Hoc, 6, 15-17.

• Feng, B. M., Sha, Y., Pei, Y. H., Hua, H. M., & Li, W. (2001). Structure determination of the constituents from Citrus grandisOsbeck. ZhongguoZhongyaozazhi= Zhongguozhongyaozazhi= China journal of Chinese materiamedica, 26(11), 764-765.

• Henquet, C., Murray, R., Linszen, D., & van Os, J. (2005). The environment and schizophrenia: the role of cannabis use. Schizophrenia bulletin, 31(3), 608-612.

• Jantan, I., Ahmad, A. S., Ahmad, A. R., Ali, N. A. M., &Ayop, N. (1996). Chemical composition of some Citrus oils from Malaysia. Journal of Essential Oil Research, 8(6), 627-632.

• Jensen, M. (2001). Trees and fruits of Southeast Asia. Orchid Press.

• Jothivel, N., Ponnusamy, S. P., Appachi, M., Singaravel, S., Rasilingam, D., Deivasigamani, K., & Thangavel, S. (2007). Anti-diabetic activity of methanol leaf extract of Costus pictus D. Don in alloxan-induced diabetic rats. Journal of Health Science, 53(6), 655-663.

• Juneja, V. K., Fan, X., Peña-Ramos, A., Diaz-Cinco, M., & Pacheco-Aguilar, R. (2006). The effect of grapefruit extract and temperature abuse on growth of Clostridium perfringens from spore inocula in marinated, sous-vide chicken products. Innovative food science & emerging technologies, 7(1-2), 100-106.

• Kharjul, A., Kharjul, M., Vilegave, K., Chandankar, P., &Gadiya, M. (2012). Pharmacognostic investigation on leaves of Citrus maxima (Burm.) Merr.(Rutaceae). International Journal of Pharmaceutical Sciences and Research, 3(12), 4913.

• KunduSen, S., Gupta, M., Mazumder, U. K., Haldar, P. K., Panda, S. P., & Bhattacharya, S. (2011). Exploration of anti-inflammatory potential of Citrus limettaRisso and Citrus maxima (J. Burm.) Merr. Pharmacologyonline, 7, 702-9.

• KunduSen, S., Saha, P., Bhattacharya, S., Bala, A., Mazumder, U. K., Gupta, M., &Haldar, P. K. (2010). Evaluation of in vitro antioxidant activity of Citrus limetta and Citrus maxima on reactive oxygen and nitrogen species. Pharmacologyonline, 3, 850-857.

• Li, S., Tan, H. Y., Wang, N., Cheung, F., Hong, M., & Feng, Y. (2018). The potential and action mechanism of polyphenols in the treatment of liver diseases. Oxidative medicine and cellular longevity, 2018.

• Madhavarao, C. N., Moffett, J. R., Moore, R. A., Viola, R. E., Namboodiri, M. A., & Jacobowitz, D. M. (2004). Immunohistochemical localization of aspartoacylase in the rat central nervous system. Journal of Comparative Neurology, 472(3), 318-329.

• Majeed, F. A., Munir, H., Rashid, R., & Zubair, M. T. (2019). Antimicrobial, cytotoxicity, mutagenicity and anti-epileptic potential of ethanol extracts of a multipurpose medicinal plant Dalbergia sissoo. Biocatalysis and Agricultural Biotechnology, 101155.

• Oboh, G., Bello, F. O., Ademosun, A. O., Akinyemi, A. J., & Adewuni, T. M. (2015). Antioxidant, hypolipidemic, and anti-angiotensin-1-converting enzyme properties of lemon (Citrus limon) and lime (Citrus aurantifolia) juices. Comparative Clinical Pathology, 24(6), 1395-1406.

• Oyedepot, A., & Babarinde, S. O. (2013). Effects of Shaddock (Citrus maxima) fruit juice on glucose tolerance and lipid profile in type-II Diabetic Rats. Chem Sci Trans, 2(1), 19-24.

• Piper, J. M. (1989). Fruits of South-east Asia: Facts and folklore. Oxford University Press.

• Radhakrishnan, A. N., Vaidyanathan, C. S., &Giri, K. V. (2013). NITROGENOUS CONSTITUENTS IN PLANTS-I. Free Amino Acids in Leaves and Leguminous Seeds. Journal of the Indian Institute of Science, 37(3), 178.

• Selsted, M. E., Tang, Y. Q., Morris, W. L., McGuire, P. A., Novotny, M. J., Smith, W., ... & Cullor, J. S. (1993). Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils. Journal of Biological Chemistry, 268(9), 6641-6648.

• Shivananda, A., Muralidhara, R. D., &Jayaveera, K. N. (2013). Analgesic and anti-inflammatory activities of Citrus maxima (J. Burm) Merr. in animal models. Res. J. Pharm. Biol. Chem. Sci., 4(2), 1800-1810.

• Taiping, Z., & Shaolin, P. (2000). Introduction to the Origin and Evolution of Pomelo and Its Distribution in China [J]. Chinese Journal of Ecology, 5.

• TAKEMURA, Y., ABE, M., JU-ICHI, M., ITO, C., HATANO, K., OMURA, M., & FURUKAWA, H. (1993). Structure of acrignine-A, the first naturally occurring acridonolignoid from Citrus plants. Chemical and pharmaceutical bulletin, 41(2), 406-407.

• Taufiq-Yap, Y. H., Peh, T. H., Ee, G. C. L., Ali, A. M., Rahmani, M., Sukari, M. A., & Muse, R. (2001). Chemical variability and some biological activities of leaf essential oils from five species of Malaysian Citrus. Oriental Journal of Chemistry, 17(3), 387-390.

• Vijaylakshmi, P., & Radha, R. (2015). Online at: www. phytopharmajournal. com. Amino Acids, 14, 19.

• Vlisidis, A. G., &Israilidis, K. I. (1998). Analysis of essential oil fractions from Greek Citrus species. ChemikaChronika, 75-78.

• Wang, D. J. (1979). Studies on the constituents of the essential oils of four aromatic flowers. Kexue Fazhan Yuekan, 7, 1036-1048.

• Zakaria, Z., Zakaria, S., & Ishak, M. A. M. (2010). Analysis of major fragrant compounds from Citrus grandis flowers extracts. Sains Malaysiana, 39(4), 565-569.

• Zheng, H., Zhang, Q., Quan, J., Zheng, Q., & Xi, W. (2016). Determination of sugars, organic acids, aroma components, and carotenoids in grapefruit pulps. Food chemistry, 205, 112-121.

• Zhou, Y., Qiao, H., Wang, L., & Liu, X. (2004). GC-MS analysis of essential oil from pomelo peel obtained in rong country. Journal of Guangxi University (Natural Science Edition), 29(1), 70-72.


  • There are currently no refbacks.